From 59 North:
Traveling South on 59, inside Loop 610,
Pass I-10, and Minute Maid Park
EXIT: McGowan
Turn RIGHT on McGowan.
Turn LEFT on La Branch (2nd light)
MPO is 3900 La Branch at Truxillo.

From I-10 East or West:
Traveling on I-10 (either direction) inside 610,
South, toward Victoria
Pass Minute Maid Park.
EXIT: McGowan
Turn RIGHT on McGowan.
Turn LEFT on La Branch (2nd light)
MPO is 3900 La Branch at Truxillo.

From 59 South:
Traveling North on 59, inside 610,
EXIT: Spur 527 (LEFT EXIT)
From the RIGHT lane of exit,
Turn RIGHT on Richmond
Turn LEFT on La Branch (4th light)
MPO is 3900 La Branch at Truxillo.

From 290:
EXIT to 610 SOUTH EXIT: 59 (Stay in Left lane of exit)
EXIT to I-10 EAST (Left turn)
EXIT: 59 South, toward Victoria (right turn onto 59)
Pass Minute Maid Park.
EXIT: McGowan
Turn RIGHT on McGowan.
Turn LEFT on La Branch (2nd light)
MPO is 3900 La Branch at Truxillo.

From I-45 North:
EXIT to 610 EAST (2nd lane from right at exit).
EXIT to 59 South, to Victoria (RIGHT turn on 59)
Pass I-10, and Minute Maid Park.
EXIT: McGowan
Turn RIGHT on McGowan.
Turn LEFT on La Branch (2nd light)
MPO is 3900 La Branch at Truxillo.

From 288 South:
Traveling North on 288 inside Loop 610,
EXIT: Southmore / Blodgett.
Turn LEFT on Southmore.
Turn RIGHT on La Branch.
MPO is 3900 La Branch at Truxillo.

From I-45 South:
Traveling North on I-45 inside 610,
EXIT Scott Street,
Stay on access road for several blks,
Turn LEFT on La Branch.
MPO is 3900 La Branch at Truxillo.